Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765465 | 0.86 | KDM4E (0.36) | KDM4EMAPKAPK2EP300KAT2BKAT8 | |
| SCHEMBL1973448 | 0.77 | P2RX1 (0.41) | KDM4EMAPKAPK2EP300KAT2BKAT8 | |
| SCHEMBL14868405 | 0.77 | ALDH1A1 (0.48) | KDM4EMAPKAPK2EP300KAT2BKAT8 | |
| SCHEMBL29788281 | 0.77 | P2RX1 (0.41) | KDM4EMAPKAPK2EP300KAT2BKAT8 | |
| SCHEMBL19489324 | 0.74 | P2RX1 (0.36) | KDM4EMAPKAPK2EP300KAT2BKAT8 | |
| SCHEMBL11710618 | 0.73 | AXL (0.35) | GAA | |
| SCHEMBL8765463 | 0.73 | CDC25B (0.33) | GAANPC1POLBFDPS | |
| SCHEMBL8765460 | 0.73 | CDC25B (0.33) | KDM4EGAACYP1A2NPC1FDPS | |
| SCHEMBL30802769 | 0.71 | KDM4C (0.48) | KDM4EGAAKDM5ANPC1POLB | |
| SCHEMBL17403402 | 0.71 | CNR1 (0.35) | KDM4EMAPKAPK2EP300KAT2BKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |