SCHEMBL8765488

SCHEMBL8765488

CC(=O)Oc1ccc(-c2cc(OC(C)=O)ccc2C(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.63
HSD17B10 Q99714 1/20 0.57
BACE1 P56817 4/20 0.53
LMNA P02545 2/20 0.53
GAA P10253 1/20 0.53
CFD P00746 1/20 0.51
GAPDH P04406 1/20 0.50
MAPT P10636 3/20 0.49
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 3/20 0.47
POLB P06746 1/20 0.47
ELANE P08246 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 3/20 0.45
RAB9A P51151 2/20 0.45
MEN1 O00255 1/20 0.45
GLA P06280 1/20 0.45
KMT2A Q03164 1/20 0.45
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10479949 0.92 BACE1 (0.64) KDM4EHSD17B10BACE1LMNAGAA
SCHEMBL9389795 0.89 HSD17B10 (0.66) KDM4EHSD17B10BACE1LMNAGAA
SCHEMBL8460794 0.85 HSD17B10 (0.56) KDM4EHSD17B10BACE1LMNAGAA
SCHEMBL9299818 0.83 HSD17B10 (0.57) KDM4EHSD17B10BACE1LMNAGAA
SCHEMBL9736751 0.82 PTPN11 (0.59) KDM4ESMN1; SMN2NPC1ALDH1A1RAB9A
SCHEMBL4360840 0.80 KDM4E (0.73) KDM4EHSD17B10LMNAGAACFD
SCHEMBL8461753 0.80 BACE1 (0.57) KDM4EHSD17B10BACE1MAPTMAPK1
SCHEMBL8457497 0.80 MAPT (0.50) KDM4EHSD17B10BACE1LMNAGAA
SCHEMBL8984342 0.80 ALDH1A1 (0.67) SMN1; SMN2ALDH1A1KMT2A
SCHEMBL18873501 0.80 HSD17B10 (0.53) KDM4EHSD17B10BACE1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4816552-A Aromatic polyester compounds and process for preparing them KOLON INDUSTRIES, INC. (KR) 1989-03-28 US claimed
EP-0427795-B1 HIGH STRENGTH POLYMER BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID AMOCO CORP (US) 1997-08-13 EP disclosed
US-5079289-A Heat resistance, molding materials, ovenware, electronic equipment AMOCO CORPORATION (US) 1992-01-07 US disclosed
US-4816552-A Aromatic polyester compounds and process for preparing them KOLON INDUSTRIES, INC. (KR) 1989-03-28 US disclosed
US-4816552-A Aromatic polyester compounds and process for preparing them KOLON INDUSTRIES, INC. (KR) 1989-03-28 US disclosed