Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765614 | 0.82 | TOP1 (0.53) | TOP1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL10053943 | 0.82 | TOP1 (0.53) | TOP1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL8779405 | 0.80 | TOP1 (0.51) | TOP1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL6023659 | 0.80 | CYP3A4 (0.52) | KDM4EALDH1A1GAAPOLBBLM | |
| SCHEMBL9744205 | 0.79 | TDP1 (0.52) | HTTPREPCELA1MAPTKDM4E | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL716891 | 0.78 | KDM4E (0.63) | TOP1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL3600800 | 0.77 | HSD17B10 (0.55) | TOP1HTTPREPCELA1MAPT | |
| SCHEMBL3293017 | 0.77 | POLB (0.51) | TOP1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL9313940 | 0.77 | TOP1 (0.57) | TOP1HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL2939004 | 0.77 | FNTA (0.55) | TOP1HTTMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |