Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041869 | 0.88 | TUBB4A (0.53) | TOP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL8765619 | 0.80 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL8765614 | 0.80 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL10053943 | 0.80 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL9042745 | 0.78 | KDM4E (0.49) | TOP1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL7959675 | 0.78 | TOP1 (0.56) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL1089019 | 0.78 | TUBB4A (0.47) | TOP1HTTKDM4EALDH1A1BLM | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL716891 | 0.77 | KDM4E (0.63) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL9360952 | 0.77 | TSHR (0.58) | TOP1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL10770955 | 0.76 | TOP1 (0.54) | TOP1HTTKDM4EALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | claimed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | claimed |
| CN-104513207-B | A kind of benzylalcohol ether compound and preparation method thereof, preparation and application | 昆药集团股份有限公司 | 2017-06-20 | — | — | CN | disclosed |
| CN-104513207-A | Benzyl alcohol ether compound, preparation method, preparation and application thereof | KUNMING PHARMACEUTICAL GROUP | 2015-04-15 | — | — | CN | disclosed |
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | disclosed |
| US-5401853-A | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 1995-03-28 | — | — | US | disclosed |
| EP-0579129-A2 | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 1994-01-19 | — | — | EP | disclosed |
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4988687-A | Thiazoleoxyimineacetamido carboxymethylpyridinium derivatives of cephalosporins | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |