Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 2/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143758 | 1.00 | ADRB3 (0.64) | ADRB3NPY5RPOLBKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8765363 | 0.99 | ADRB3 (0.63) | ADRB3NPY5RPOLBKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8765375 | 0.99 | ADRB3 (0.63) | ADRB3NPY5RPOLBKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8765990 | 0.99 | ADRB3 (0.63) | ADRB3NPY5RPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL8766365 | 0.97 | ADRB3 (0.61) | ADRB3NPY5RPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL8765124 | 0.96 | ADRB3 (0.59) | ADRB3NPY5RPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL9443702 | 0.94 | ADRB3 (0.56) | ADRB3NPY5RPOLBGRIN2BADRB1 | |
| Hydrochloric Acid SCHEMBL9443699 | 0.93 | ADRB3 (0.56) | ADRB3NPY5RPOLBGRIN2BADRB1 | |
| SCHEMBL5143979 | 0.89 | ADRB3 (0.51) | ADRB3NPY5RKDM4ESMN1; SMN2HPGD | |
| SCHEMBL5146479 | 0.86 | GRIN2B (0.48) | ADRB3KDM4ESMN1; SMN2HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |