Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9443699 | 0.99 | ADRB3 (0.56) | ADRB3GRIN2BNPY5RADRB1POLB | |
| SCHEMBL5143758 | 0.94 | ADRB3 (0.64) | ADRB3GRIN2BNPY5RADRB1POLB | |
| SCHEMBL8765648 | 0.94 | ADRB3 (0.64) | ADRB3GRIN2BNPY5RADRB1POLB | |
| SCHEMBL8766365 | 0.93 | ADRB3 (0.61) | ADRB3GRIN2BNPY5RADRB1POLB | |
| Hydrochloric Acid SCHEMBL8765375 | 0.93 | ADRB3 (0.63) | ADRB3GRIN2BNPY5RADRB1POLB | |
| Hydrochloric Acid SCHEMBL8765363 | 0.93 | ADRB3 (0.63) | ADRB3GRIN2BNPY5RADRB1POLB | |
| Hydrochloric Acid SCHEMBL8765990 | 0.93 | ADRB3 (0.63) | ADRB3GRIN2BNPY5RADRB1POLB | |
| SCHEMBL8765124 | 0.90 | ADRB3 (0.59) | ADRB3GRIN2BNPY5RPOLB | |
| SCHEMBL9513692 | 0.89 | BRD4 (0.50) | ADRB3GRIN2BDRD2DRD3 | |
| SCHEMBL9513902 | 0.89 | GRIN2B (0.48) | ADRB3GRIN2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347313-B1 | 2-Amino-7-hydroxytetraline ethers | SANOFI ELF (FR) | 1993-12-15 | — | — | EP | claimed |
| US-5202466-A | 2-amino-7-hydroxytetraline ethers | SANOFI (FR) | 1993-04-13 | — | — | US | claimed |
| EP-0347313-A2 | 2-Amino-7-hydroxytetraline ethers | ELF SANOFI (FR) | 1989-12-20 | — | — | EP | claimed |
| EP-0347313-B1 | 2-Amino-7-hydroxytetraline ethers | SANOFI ELF (FR) | 1993-12-15 | — | — | EP | disclosed |
| EP-0347313-A2 | 2-Amino-7-hydroxytetraline ethers | ELF SANOFI (FR) | 1989-12-20 | — | — | EP | disclosed |