Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377390 | 0.89 | SLC22A6 (0.55) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL6198832 | 0.89 | BACE1 (0.57) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL15495899 | 0.88 | KDM4E (0.50) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL19558336 | 0.86 | ELANE (0.58) | KDM4EMAPTMAPK1CYP3A4ELANE | |
| SCHEMBL15495950 | 0.86 | ELANE (0.50) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL21921357 | 0.84 | CYP3A4 (0.58) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL14351068 | 0.84 | KDM4E (0.46) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL1866980 | 0.83 | KDM4E (0.67) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL29440769 | 0.83 | KDM4E (0.67) | KDM4EMAPTMAPK1CYP3A4LMNA | |
| SCHEMBL50809 | 0.83 | CYP3A4 (0.62) | KDM4EMAPTMAPK1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |