SCHEMBL1866980

SCHEMBL1866980

CC(=O)Oc1ccc(OC(C)=O)c(OC(C)=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.67
TSHR P16473 2/20 0.60
RAB9A P51151 2/20 0.60
GAA P10253 2/20 0.60
ALDH1A1 P00352 1/20 0.60
MAPT P10636 4/20 0.59
MAPK1 P28482 2/20 0.59
LMNA P02545 4/20 0.54
CYP3A4 P08684 3/20 0.52
KMT2A Q03164 3/20 0.50
PKM P14618 2/20 0.50
MEN1 O00255 2/20 0.50
BACE1 P56817 1/20 0.50
ACHE P22303 1/20 0.50
NPC1 O15118 1/20 0.50
HTT P42858 1/20 0.50
ALOX12 P18054 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29440769 1.00 KDM4E (0.67) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL2729632 0.90 TSHR (0.64) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL11793587 0.88 BACE1 (0.61) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL5885254 0.87 ALOX15 (0.57) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL9150083 0.85 KDM4E (0.56) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL9788674 0.85 CYP3A4 (0.51) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL178917 0.84 KDM4E (0.53) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL9477940 0.84 MAPT (0.60) KDM4ETSHRRAB9AGAAALDH1A1
SCHEMBL153056 0.83 CA12 (0.59) KDM4ETSHRGAAALDH1A1MAPT
SCHEMBL8765701 0.83 KDM4E (0.62) KDM4ETSHRRAB9AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3529356-A1 CONCERTED PROCESSES FOR FORMING 1,2,4-TRIHYDROXYBENZENE FROM HYDROQUINONE Lockheed Martin Energy, LLC (US) 2019-08-28 EP claimed
US-10065977-B2 Concerted processes for forming 1,2,4-trihydroxybenzene from hydroquinone LOCKHEED MARTIN ADVANCED ENERGY STORAGE, LLC (US) 2018-09-04 US claimed
US-9963476-B2 Antioxidant compound having anti atherosclerotic effect and preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-05-08 US claimed
WO-2018075080-A1 CONCERTED PROCESSES FOR FORMING 1,2,4-TRIHYDROXYBENZENE FROM HYDROQUINONE LOCKHEED MARTIN ADVANCED ENERGY STORAGE, LLC (US) 2018-04-26 WO claimed
US-20180105544-A1 CONCERTED PROCESSES FOR FORMING 1,2,4-TRIHYDROXYBENZENE FROM HYDROQUINONE LOCKHEED MARTIN ENERGY, LLC 2018-04-19 US claimed
US-20170240577-A1 ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-08-24 US claimed
US-20160244470-A1 ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-08-25 US claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
US-5512454-A Enzymatic acylation of 3-hydroxymethyl cephalosporins BRISTOL-MYERS SQUIBB COMPANY (US) 1996-04-30 US claimed
EP-0667396-A1 Enzymatic acylation of 3-hydroxymethyl cephalosporins BRISTOL-MYERS SQUIBB COMPANY (US) 1995-08-16 EP claimed
JP-10138645-A None JP disclosed
EP-3745105-B1 TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME HITACHI LTD (JP) 2025-08-27 EP disclosed
US-12247239-B2 Chemo-enzymatic process for the preparation of homopropargylic alcohol COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2025-03-11 US disclosed
US-20240400247-A1 TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-12-05 US disclosed
EP-4431889-A1 TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD Hitachi Industrial Equipment Systems Co., Ltd. (JP) 2024-09-18 EP disclosed
US-4264509-A STORAGE STABILITY FOR FOODS CONTAINING OILS AND FATS Z-L LIMITED PARTNERSHIP (US) 1981-04-28 US disclosed
WO-1980002098-A1 ISOFLAVONES AND RELATED COMPOUNDS,METHODS OF PREPARING AND USING AND ANTIOXIDANT COMPOSITIONS CONTAINING SAME PARTNERSHIP LTD (US) 1980-10-16 WO disclosed
US-4054413-A PREFORMED SOLUTION OF TRIACETATE OF A BENZENETRIOL, A P-PHENYLENEDIAMINE CLAIROL INCORPORATED (US) 1977-10-18 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed
US-RE29148-E Color photographic diffusion transfer process FUJI PHOTO FILM CO., LTD. (JA) 1977-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10065977-B2 Concerted processes for forming 1,2,4-trihydroxybenzene from hydroquinone HAAO, HAO2, NQO1 KDM4E 1217/4885TSHR 4477/4885RAB9A 2870/4885
US-20160244470-A1 ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF ECHS1, ECE2, KEAP1 KDM4E 1686/4885TSHR 4843/4885RAB9A 1418/4885
US-20180105544-A1 CONCERTED PROCESSES FOR FORMING 1,2,4-TRIHYDROXYBENZENE FROM HYDROQUINONE HAAO, HAO2, NQO1 KDM4E 1217/4885TSHR 4477/4885RAB9A 2870/4885
US-20170240577-A1 ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF ECHS1, ECE2, KEAP1 KDM4E 1657/4885TSHR 4843/4885RAB9A 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.