Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.82 |
| ▸ | DRD3 | P35462 | 7/20 | 0.82 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765903 | 1.00 | DRD2 (0.82) | DRD2DRD3KDM1AACHEDRD4 | |
| SCHEMBL5144002 | 1.00 | DRD2 (0.82) | DRD2DRD3KDM1AACHEDRD4 | |
| Hydrochloric Acid SCHEMBL8765573 | 0.98 | DRD2 (0.79) | DRD2DRD3KDM1AACHEDRD4 | |
| Hydrochloric Acid SCHEMBL8765567 | 0.98 | DRD2 (0.79) | DRD2DRD3KDM1AACHEDRD4 | |
| Hydrochloric Acid SCHEMBL8765944 | 0.98 | DRD2 (0.79) | DRD2DRD3KDM1AACHEDRD4 | |
| SCHEMBL5678226 | 0.94 | DRD2 (0.71) | DRD2DRD3KDM1AACHEDRD4 | |
| SCHEMBL267102 | 0.90 | DRD2 (1.00) | DRD2DRD3ACHEDRD4MTNR1A | |
| SCHEMBL268141 | 0.90 | DRD2 (1.00) | DRD2DRD3ACHEDRD4MTNR1A | |
| SCHEMBL354006 | 0.90 | DRD2 (1.00) | DRD2DRD3ACHEDRD4MTNR1A | |
| Hydrochloric Acid SCHEMBL3001108 | 0.89 | DRD2 (0.97) | DRD2DRD3ACHEDRD4MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |