Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577200 | 0.82 | GRIN2B (0.63) | GRIN2BKDM4EALDH1A1BCHEACHE | |
| SCHEMBL8912128 | 0.82 | GRIN2B (0.68) | GRIN2BKDM4EALDH1A1BCHEACHE | |
| SCHEMBL8185940 | 0.81 | GRIN2B (0.86) | GRIN2BKDM4EALDH1A1BCHEACHE | |
| SCHEMBL11553032 | 0.81 | GRIN2B (0.61) | GRIN2BBCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL8176663 | 0.81 | GRIN2B (0.67) | GRIN2BKDM4EALDH1A1BCHEACHE | |
| Hydrochloric Acid SCHEMBL8187601 | 0.80 | GRIN2B (0.84) | GRIN2BBCHEACHEBACE1POLB | |
| SCHEMBL8185330 | 0.77 | KDM4E (0.71) | GRIN2BKDM4EALDH1A1BCHEACHE | |
| SCHEMBL8766323 | 0.77 | GRIN2B (0.71) | GRIN2BKDM4EALDH1A1BCHEACHE | |
| SCHEMBL18339371 | 0.75 | HSP90AA1 (0.49) | GRIN2BALDH1A1 | |
| SCHEMBL6616312 | 0.75 | HSP90AA1 (0.49) | GRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |