Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.71 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185940 | 0.86 | GRIN2B (0.86) | GRIN2BBCHEACHEBACE1POLB | |
| Hydrochloric Acid SCHEMBL8187601 | 0.85 | GRIN2B (0.84) | GRIN2BBCHEACHEBACE1POLB | |
| SCHEMBL11549987 | 0.81 | GRIN2B (0.56) | GRIN2BBCHEACHEBACE1DRD2 | |
| SCHEMBL11523246 | 0.80 | GRIN2B (0.45) | GRIN2BACHEALDH1A1DRD2 | |
| SCHEMBL5145409 | 0.80 | GRIN2B (0.74) | GRIN2BBCHEACHEBACE1POLB | |
| SCHEMBL8186614 | 0.78 | GRIN2B (0.73) | GRIN2BBCHEACHEBACE1POLB | |
| Hydrochloric Acid SCHEMBL8187663 | 0.77 | GRIN2B (0.71) | GRIN2BBCHEACHEBACE1POLB | |
| SCHEMBL8765798 | 0.77 | GRIN2B (0.70) | GRIN2BBCHEACHEBACE1POLB | |
| SCHEMBL8912128 | 0.75 | GRIN2B (0.68) | GRIN2BBCHEACHEBACE1POLB | |
| SCHEMBL8192687 | 0.75 | GRIN2B (0.67) | GRIN2BBCHEACHEBACE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |