Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142005 | 0.96 | GRIN2B (0.59) | GRIN2BFYNDRD3DRD2DRD4 | |
| SCHEMBL8765625 | 0.96 | GRIN2B (0.59) | GRIN2BFYNDRD3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8765161 | 0.95 | GRIN2B (0.58) | GRIN2BFYNDRD3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL5144064 | 0.95 | GRIN2B (0.58) | GRIN2BFYNDRD3DRD2DRD4 | |
| SCHEMBL5146440 | 0.91 | GRIN2B (0.59) | GRIN2BFYNDRD3DRD2DRD4 | |
| SCHEMBL9306071 | 0.91 | GRIN2B (0.71) | GRIN2BFYNDRD3DRD2DRD4 | |
| SCHEMBL9304253 | 0.91 | GRIN2B (0.71) | GRIN2BFYNDRD3DRD2DRD4 | |
| SCHEMBL6133948 | 0.91 | GRIN2B (0.71) | GRIN2BFYNDRD3DRD2DRD4 | |
| Bromide SCHEMBL9304413 | 0.90 | GRIN2B (0.69) | GRIN2BFYNDRD3DRD2DRD4 | |
| Bromide SCHEMBL9303647 | 0.90 | GRIN2B (0.69) | GRIN2BFYNDRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| EP-0787754-A2 | Blocked aliphatic diisocyanates or diisocyanate-adducts | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-08-06 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |