Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.71 |
| ▸ | DRD3 | P35462 | 4/20 | 0.63 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | FYN | P06241 | 1/20 | 0.62 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304253 | 1.00 | GRIN2B (0.71) | GRIN2BDRD3DRD2DRD4FYN | |
| SCHEMBL6133948 | 1.00 | GRIN2B (0.71) | GRIN2BDRD3DRD2DRD4FYN | |
| Bromide SCHEMBL9304413 | 0.99 | GRIN2B (0.69) | GRIN2BDRD3DRD2DRD4FYN | |
| Bromide SCHEMBL9303647 | 0.99 | GRIN2B (0.69) | GRIN2BDRD3DRD2DRD4FYN | |
| Bromide SCHEMBL9304418 | 0.99 | GRIN2B (0.69) | GRIN2BDRD3DRD2DRD4FYN | |
| SCHEMBL5142005 | 0.92 | GRIN2B (0.59) | GRIN2BDRD3DRD2DRD4FYN | |
| SCHEMBL8765625 | 0.92 | GRIN2B (0.59) | GRIN2BDRD3DRD2DRD4FYN | |
| Hydrochloric Acid SCHEMBL8765161 | 0.91 | GRIN2B (0.58) | GRIN2BDRD3DRD2DRD4FYN | |
| SCHEMBL8765804 | 0.91 | GRIN2B (0.58) | GRIN2BDRD3DRD2DRD4FYN | |
| Hydrochloric Acid SCHEMBL5144064 | 0.91 | GRIN2B (0.58) | GRIN2BDRD3DRD2DRD4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312961-A | 2-amino-7-hydroxytetralin carboxylalkyl ethers | ELF SANOFI (FR) | 1994-05-17 | — | — | US | disclosed |
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | disclosed |
| EP-0383686-A1 | 2-Amino-7-hydroxytetraline carboxyalkyl ethers | ELF SANOFI (FR) | 1990-08-22 | — | — | EP | disclosed |