SCHEMBL8765972

SCHEMBL8765972

C=C(C)C(=O)OC(Cl)(Cl)CP(=O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 3/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3098698 0.79 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL1805268 0.76 ALDH1A1 (0.34) ALDH1A1TSHRTHRB
SCHEMBL11540953 0.76 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL614376 0.76 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL6889390 0.75 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL8975811 0.74 GRM4 (0.36) ALDH1A1TSHR
SCHEMBL14955128 0.74 TSHR (0.35) ALDH1A1TSHRTHRB
SCHEMBL11682881 0.72 TSHR (0.38) ALDH1A1TSHRTHRB
SCHEMBL1805860 0.71 TSHR (0.40) TSHR
SCHEMBL8957367 0.71 ALDH1A1 (0.44) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0776320-A1 FLUORINATED ACRYLIC MONOMERS CONTAINING URETHANE GROUPS AND THEIR POLYMERS W.L. GORE & ASSOCIATES, INC. (US) 1997-06-04 EP disclosed
EP-0582667-B1 FLUOROACRYLATE MONOMERS AND POLYMERS, PROCESSES FOR PREPARING THE SAME AND THEIR USE MINNESOTA MINING & MFG (US) 1996-06-26 EP disclosed
WO-1996005172-A1 FLUORINATED ACRYLIC MONOMERS CONTAINING URETHANE GROUPS AND THEIR POLYMERS W.L. GORE & ASSOCIATES, INC. (US) 1996-02-22 WO disclosed
US-5446118-A A fluoropolymer protective coating; water and oil repellancy W. L. GORE & ASSOCIATES, INC. (US) 1995-08-29 US disclosed
US-5344956-A Water and oil repellant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-09-06 US disclosed
US-5216097-A Polymerization product of a diisocyanate with a perfluoro compound and acrylic esters of a three hydroxyl groups containing compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-01 US disclosed
WO-1992019663-A1 FLUOROACRYLATE MONOMERS AND POLYMERS, PROCESSES FOR PREPARING THE SAME AND THEIR USE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-11-12 WO disclosed
US-5144056-A Finishing leather, acrylic esters containing carbamate groups ATOCHEM (FR) 1992-09-01 US disclosed
US-4920190-A ACRYLIC ESTER HOMO-AND COPOLYMERS; OIL AND WATER RESISTANT, FOR LEATHER ATOCHEM (FR) 1990-04-24 US disclosed
US-4778915-A WATER REPELLANT, OIL REPELLANT PROTECTIVE COATINGS FOR LEATHER ATOCHEM (FR) 1988-10-18 US disclosed
US-3969440-A FIREPROOFING SCOTT PAPER COMPANY (US) 1976-07-13 US disclosed