Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL8765979

CC(c1cccc(N)c1)S(=O)(=O)[O-].CCCC[N+](CCCC)(CCCC)CCCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CPN1 P15169 1/20 0.34
CPB2 Q96IY4 1/20 0.34
ALDH1A1 P00352 1/20 0.33
ASAH1 Q13510 1/20 0.33
ACER2 Q5QJU3 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NR1I2 O75469 1/20 0.32
LMNA P02545 1/20 0.32
GRM2 Q14416 1/20 0.32
SLC22A1 O15245 1/20 0.32
CA12 O43570 1/20 0.31
CA4 P22748 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL8765993 0.87 TSHR (0.38) TSHRCA1CA2CA9CPN1
Tetrabuthylammonium SCHEMBL8860033 0.81 KMT2A (0.45) TSHRALDH1A1LMNA
Tetrabuthylammonium SCHEMBL9062845 0.78 LMNA (0.46) TSHRCA1CA2CA9ALDH1A1
Tetrabuthylammonium SCHEMBL8870070 0.76 TSHR (0.39) TSHRCA1CA2CA9LMNA
Tetrabuthylammonium SCHEMBL29130277 0.73 KDM4E (0.42) CA1CA2CA9ALDH1A1ASAH1
Tetrabuthylammonium SCHEMBL9062848 0.72 TSHR (0.65) TSHRCA1CA2CA9ALDH1A1
Tetrabuthylammonium SCHEMBL8870078 0.71 TSHR (0.40) TSHRCA1CA2CA9ALDH1A1
SCHEMBL6429607 0.71 TSHR (0.49) TSHRCA2CPN1CPB2GRM2
SCHEMBL21124173 0.70 TSHR (0.44) TSHRCA1CA2CA9CPN1
Tetrabuthylammonium SCHEMBL8860036 0.70 KMT2A (0.47) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659175-B1 OPTICALLY ACTIVE ALKYLAMMONIUM (AMINO-3 PHENYL)-1 ETHANESULFONATE DERIVATIVES, PREPARATION AND USE THEREOF RHONE POULENC RORER SA (FR) 1997-08-13 EP claimed
US-5523469-A REACTING ALKALI METAL SULFITE ON 1-(1-BROMOETHYL)-3-NITROBENZENE; CONVERSION TO POTASSIUM SALT; CONVERSION TO BENZYLQUINIUM SALT; THEN QUATERNIZATION RHONE-POULENC RORER S.A. (FR) 1996-06-04 US claimed
US-5663204-A CHOLECYSTOKININ AND GASTRIN ANTAGONIST FOR APPETITE REGULATORS, GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS RHONE-POULENC RORER S.A. (FR) 1997-09-02 US disclosed
US-5610144-A CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS RHONE-POULENC RORER S.A. (FR) 1997-03-11 US disclosed
US-5523469-A REACTING ALKALI METAL SULFITE ON 1-(1-BROMOETHYL)-3-NITROBENZENE; CONVERSION TO POTASSIUM SALT; CONVERSION TO BENZYLQUINIUM SALT; THEN QUATERNIZATION RHONE-POULENC RORER S.A. (FR) 1996-06-04 US disclosed