Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.44 |
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850349 | 0.93 | PTGS1 (0.48) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL10850361 | 0.93 | PTGS1 (0.48) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL10805334 | 0.92 | NR1I2 (0.47) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL5712656 | 0.91 | NR1I2 (0.47) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL5712657 | 0.91 | NR1I2 (0.47) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL9201934 | 0.91 | NR1I2 (0.47) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL10848830 | 0.91 | NR1I2 (0.46) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL8766948 | 0.91 | NR1I2 (0.42) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL10848834 | 0.91 | NR1I2 (0.46) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL10943928 | 0.90 | NR1I2 (0.42) | NR1I2PGRPPARGESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504404-B1 | PROCESS FOR PRODUCING 3-SUBSTITUTED THIO-3-CEPHEM COMPOUND | MEIJI SEIKA KAISHA (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5294705-A | Process for the preparation of a 3-substituted thio-3-cephem compound | MEIJI SEIKA KAISHA, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0504404-A1 | PROCESS FOR PRODUCING 3-SUBSTITUTED THIO-3-CEPHEM COMPOUND | MEIJI SEIKA KAISHA LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |