Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201934 | 1.00 | NR1I2 (0.47) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL5712657 | 1.00 | NR1I2 (0.47) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9622955 | 0.96 | NR1I2 (0.49) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9361968 | 0.96 | NR1I2 (0.49) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10563345 | 0.96 | NR1I2 (0.49) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9361977 | 0.96 | NR1I2 (0.49) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10805334 | 0.95 | NR1I2 (0.47) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10848834 | 0.94 | NR1I2 (0.46) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL10848830 | 0.94 | NR1I2 (0.46) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9370289 | 0.92 | NR1I2 (0.51) | NR1I2PPARGPGRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325923-B1 | CEPHEM COMPOUNDS AND ESBL-DETECTING REAGENTS CONTAINING THE SAME | ZENYAKU KOGYO KK (JP) | 2006-12-06 | — | — | EP | disclosed |
| US-6897304-B2 | Cephem compounds and ESBL-detecting reagents containing the same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2005-05-24 | — | — | US | disclosed |
| US-20040019202-A1 | Cephem compounds and esbl-detecting reagents containing the same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-01-29 | — | — | US | disclosed |
| EP-1325923-A1 | CEPHEM COMPOUNDS AND ESBL-DETECTING REAGENTS CONTAINING THE SAME | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-0452987-B1 | Isoindoline derivatives | BANYU PHARMA CO LTD (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0186187-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0182210-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4677100-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019202-A1 | Cephem compounds and esbl-detecting reagents containing the same | MRPL21, CLIC1, QSOX1 | NR1I2 1429/4885PPARG 4849/4885PGR 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.