Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766027 | 0.90 | CHRM1 (0.42) | OPRM1HDAC4CHRM1CHRM2CHRM4 | |
| SCHEMBL8766324 | 0.89 | CHRM1 (0.39) | OPRM1CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8766901 | 0.88 | OPRM1 (0.42) | OPRM1HDAC4HSD11B1HSD11B2OPRK1 | |
| SCHEMBL8766915 | 0.88 | CHRM1 (0.38) | OPRM1CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8765885 | 0.88 | CHRM1 (0.38) | OPRM1CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8766470 | 0.88 | CHRM1 (0.38) | OPRM1CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8766611 | 0.82 | HDAC4 (0.36) | OPRM1HDAC4HRH3HSD11B1HSD11B2 | |
| SCHEMBL8766466 | 0.82 | HDAC4 (0.44) | OPRM1HDAC4CHRM1CHRM2CHRM4 | |
| SCHEMBL8767206 | 0.81 | HRH3 (0.35) | OPRM1HDAC4HRH3HSD11B1CYP2C9 | |
| SCHEMBL8094316 | 0.77 | OPRM1 (0.44) | OPRM1CHRM1CHRM2DRD4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |