Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767096 | 0.99 | KCNH2 (0.35) | HRH3OPRK1OPRM1OPRL1KCNH2 | |
| SCHEMBL8766290 | 0.99 | KCNH2 (0.35) | HRH3OPRK1OPRM1OPRL1KCNH2 | |
| SCHEMBL8766518 | 0.99 | KCNH2 (0.35) | HRH3OPRK1OPRM1OPRL1KCNH2 | |
| SCHEMBL8766392 | 0.96 | HRH3 (0.37) | HRH3OPRK1OPRM1OPRL1DDB1 | |
| SCHEMBL8766347 | 0.90 | CYP3A4 (0.36) | HRH3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL8766387 | 0.90 | OPRK1 (0.39) | HRH3OPRK1OPRM1OPRL1DDB1 | |
| SCHEMBL8767246 | 0.89 | CYP3A4 (0.38) | HRH3KCNH2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8766430 | 0.89 | CYP3A4 (0.38) | HRH3KCNH2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8766579 | 0.89 | CYP3A4 (0.38) | HRH3KCNH2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8766440 | 0.86 | HRH3 (0.39) | HRH3OPRK1OPRM1OPRL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |