SCHEMBL876650

SCHEMBL876650

C=C(C)C(=O)OCCCC[SiH2]C(OCC)OCC

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
THRB P10828 1/20 0.49
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21066734 0.98 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537548 0.98 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27511005 0.98 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL137795 0.95 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22115856 0.90 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL65281 0.89 THRB (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29022840 0.88 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22115820 0.88 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28350060 0.87 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537856 0.86 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
CN-118459684-A Impact modifier, preparation method and modified resin 中化学科学技术研究有限公司 2024-08-09 CN disclosed
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN disclosed
EP-4153682-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-06-05 EP disclosed
EP-4153681-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-05-29 EP disclosed
CN-117120538-A Thermoplastic resin composition and molded article thereof 大科能宇菱通株式会社 2023-11-24 CN disclosed
CN-117083343-A Thermoplastic resin composition and molded article 大科能宇菱通株式会社 2023-11-17 CN disclosed
CN-116997583-A Polyorganosiloxane-containing polymer, composition and molded body 三菱化学株式会社 2023-11-03 CN disclosed
CN-116848197-A Resin composition and molded article 三菱化学株式会社 2023-10-03 CN disclosed
US-11708455-B2 Flame-retardant polycarbonate composition COVESTRO DEUTSCHLAND AG (DE) 2023-07-25 US disclosed
EP-1026205-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE Teijin Chemicals, Ltd. (JP) 2000-08-09 EP disclosed
WO-2000039210-A1 POLYCARBONATE RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2000-07-06 WO disclosed
CN-1228799-A Moulding compound consisting of polycarbonate mixture and siloxane reticular rubber BASF AG (DE) 1999-09-15 CN disclosed
CN-1192754-A Polymer composition for graft copolymers as well as mixtures thereof and thermoplastic compounds contg. same BASF AG (DE) 1998-09-09 CN disclosed
CN-1192755-A Polymer compositions for graft copolymers as well as mixtures thereof and thermoplastic compounds contg. same BASF AG (DE) 1998-09-09 CN disclosed
CN-1181395-A Thermalplastic resin compsn. KANEGAFUCHI CHEMICAL IND (JP) 1998-05-13 CN disclosed
CN-1167783-A Compounded rubber particle and compounded rubber graft copolymer particle KANEGAFUCHI CHEMICAL IND (JP) 1997-12-17 CN disclosed
EP-0728161-A1 A POLYCARBONATE RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 1996-08-28 EP disclosed
WO-1996007704-A1 A POLYCARBONATE RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 1996-03-14 WO disclosed
EP-0369376-A2 Flame retardant polyphenylene ether resin composition MITSUBISHI RAYON CO., LTD. (JP) 1990-05-23 EP disclosed