SCHEMBL8766641

SCHEMBL8766641

CCCc1cc(Cc2ccc(C3(c4ccc(Cc5ccc(N)c(CCC)c5)cc4)CCC(C)CC3)cc2)ccc1N

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SKP2 Q13309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766603 0.90 ALDH1A1 (0.33) ALDH1A1CYP3A4KDM4EMEN1POLB
SCHEMBL8766556 0.88 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8766410 0.86 ALDH1A1 (0.42) ALDH1A1CYP3A4KDM4EMEN1POLB
SCHEMBL8945000 0.82 SPHK1 (0.41) ALDH1A1CYP3A4
SCHEMBL8766334 0.82 SKP2 (0.39) ALDH1A1CYP3A4KDM4EMEN1POLB
SCHEMBL8766408 0.81 ALDH1A1 (0.33) ALDH1A1CYP3A4KDM4EMEN1POLB
SCHEMBL8766435 0.79 ALDH1A1 (0.31) ALDH1A1KDM4EPOLBGAAMAPT
SCHEMBL8766407 0.79 ALDH1A1 (0.33) ALDH1A1CYP3A4
SCHEMBL1305036 0.78 ALDH1A1 (0.47) ALDH1A1CYP3A4
SCHEMBL1100722 0.78 ALDH1A1 (0.47) ALDH1A1CYP3A4KDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed