SCHEMBL8766653

SCHEMBL8766653

CCCCCCCCCCCCCCCCCCNC(=O)N(CCCCCCCCCCCCCCCCCC)C(=O)CCCCCCCCCCCC

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.51
DNM1 Q05193 2/20 0.49
CASP2 P42575 1/20 0.49
EPHX1 P07099 7/20 0.48
NAAA Q02083 1/20 0.46
KDM5A P29375 5/20 0.45
PHF8 Q9UPP1 3/20 0.45
KDM4C Q9H3R0 3/20 0.45
PLA2G2A P14555 1/20 0.45
FAAH O00519 1/20 0.44
KDM5C P41229 1/20 0.43
KDM5B Q9UGL1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766660 1.00 EPHX2 (0.51) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL8767024 1.00 EPHX2 (0.51) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL8767408 1.00 EPHX2 (0.51) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL12716091 0.91 DNM1 (0.59) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL15159475 0.88 EPHX1 (0.50) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL13868080 0.88 EPHX1 (0.57) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL20623094 0.88 EPHX1 (0.57) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL13097658 0.88 EPHX1 (0.57) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL27543496 0.85 EPHX1 (0.46) EPHX2DNM1CASP2EPHX1NAAA
SCHEMBL15159447 0.83 EPHX1 (0.52) EPHX2DNM1CASP2EPHX1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0567012-B1 Reversible heat-sensitive recording medium TOMOEGAWA PAPER CO LTD (JP) 1997-08-13 EP disclosed
US-5273950-A Low-molecular organic compounds dispersed in a supported macromolecular resin; at least one long chain alkyl compound and saturated aliphatic bisamide TOMOEGAWA PAPER CO., LTD. (JP) 1993-12-28 US disclosed
EP-0567012-A2 Reversible heat-sensitive recording medium TOMOEGAWA PAPER CO. LTD. (JP) 1993-10-27 EP disclosed