SCHEMBL8766680

SCHEMBL8766680

COc1ccc(C2(c3ccc(Oc4ccc(S(=O)(=O)c5ccc(Oc6ccc(C(=O)c7ccc(C)cc7)cc6)cc5)cc4)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 3/20 0.42
MMP2 P08253 3/20 0.42
MMP9 P14780 3/20 0.42
MMP8 P22894 3/20 0.42
MMP12 P39900 3/20 0.42
MMP13 P45452 3/20 0.42
MMP14 P50281 3/20 0.42
MMP16 P51512 3/20 0.42
MMP3 P08254 2/20 0.42
TP53 P04637 2/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17808969 0.96 HTT (0.53) HTTSMN1; SMN2TDP1L3MBTL1LMNA
SCHEMBL13321958 0.92 HTT (0.57) HTTSMN1; SMN2TDP1L3MBTL1LMNA
SCHEMBL13321950 0.92 RAB9A (0.43) LMNAMMP13MAPTALDH1A1NPC1
SCHEMBL9914257 0.92 HTT (0.57) HTTSMN1; SMN2TDP1L3MBTL1LMNA
SCHEMBL12341727 0.92 HTT (0.57) HTTSMN1; SMN2TDP1L3MBTL1LMNA
SCHEMBL13882640 0.92 RAB9A (0.43) LMNAMMP13MAPTALDH1A1NPC1
SCHEMBL9914259 0.92 RAB9A (0.43) LMNAMMP13MAPTALDH1A1NPC1
SCHEMBL14514249 0.92 RAB9A (0.43) LMNAMMP13MAPTALDH1A1NPC1
SCHEMBL15760410 0.92 RAB9A (0.43) LMNAMMP13MAPTALDH1A1NPC1
SCHEMBL822951 0.88 SRD5A2 (0.46) SMN1; SMN2LMNAMMP13MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8916672-B2 Transparent polyarylene ether polymer with high heat resistance and method for preparing the same ICUF-HYU (Industry-University Cooperation Foundation Hanyang University) (KR) 2014-12-23 US disclosed
US-8916672-B2 Transparent polyarylene ether polymer with high heat resistance and method for preparing the same ICUF-HYU (Industry-University Cooperation Foundation Hanyang University) (KR) 2014-12-23 US disclosed
US-20120130041-A1 Transparent Polyarylene Ether Polymer With High Heat Resistance And Method For Preparing The Same IUCF-HYU (Industry-University Coperation Foundatio Hanyang University (KR) 2012-05-24 US disclosed