Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484805 | 0.77 | DRD1 (0.38) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8484803 | 0.77 | DRD1 (0.38) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8473216 | 0.76 | JAK2 (0.38) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL7201360 | 0.74 | DRD1 (0.34) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL7201358 | 0.74 | DRD1 (0.34) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8487015 | 0.74 | IRAK4 (0.43) | TSHRJAK3 | |
| SCHEMBL8369812 | 0.73 | DRD1 (0.33) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8484084 | 0.71 | JAK3 (0.34) | DRD1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8487264 | 0.70 | CDK5 (0.36) | — | |
| SCHEMBL8487263 | 0.70 | CDK5 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787128-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011913-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |