Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487583 | 0.95 | L3MBTL1 (0.44) | IRAK4L3MBTL1RAB9ACYP2C19CYP1A2 | |
| SCHEMBL8482284 | 0.77 | L3MBTL1 (0.46) | IRAK4L3MBTL1RAB9ACYP2C19CYP1A2 | |
| SCHEMBL8482286 | 0.77 | L3MBTL1 (0.46) | IRAK4L3MBTL1RAB9ACYP2C19CYP1A2 | |
| SCHEMBL23707456 | 0.76 | HRH1 (0.47) | IRAK4L3MBTL1RAB9ACYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL2797523 | 0.75 | JAK3 (0.48) | L3MBTL1RAB9ACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL8766688 | 0.74 | DRD1 (0.34) | TSHRJAK3 | |
| SCHEMBL8767908 | 0.74 | CYP1A2 (0.50) | IRAK4CYP2C19CYP1A2TSHRLMNA | |
| SCHEMBL17209403 | 0.74 | IRAK4 (0.57) | IRAK4L3MBTL1CYP2C19JAK3LMNA | |
| SCHEMBL8486572 | 0.73 | L3MBTL1 (0.45) | IRAK4L3MBTL1RAB9ACYP2C19CYP1A2 | |
| SCHEMBL8486645 | 0.72 | CYP1A2 (0.48) | IRAK4CYP2C19CYP1A2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889012-A | INSECTICIDE, ACARICIDES, FUNGICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0787128-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011913-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |