SCHEMBL8766848

SCHEMBL8766848

Cc1ccc(C(=O)c2ccc(Oc3ccc(S(=O)(=O)c4ccc(Oc5ccc6cc(C)ccc6c5)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
TDP1 Q9NUW8 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.55
POLB P06746 2/20 0.50
APEX1 P27695 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
GFER P55789 1/20 0.47
ALDH1A1 P00352 3/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
MMP13 P45452 1/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP2C9 P11712 4/20 0.43
CYP2C19 P33261 3/20 0.43
CYP1A2 P05177 2/20 0.43
HSD17B1 P14061 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13670304 0.97 HTT (0.60) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL12769549 0.90 LMNA (0.55) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL12769552 0.90 HTT (0.73) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL12769554 0.90 HTT (0.67) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL822651 0.90 HTT (0.67) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL822865 0.90 HTT (0.67) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL12769546 0.87 HTT (0.69) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL12769544 0.87 CYP2A6 (0.53) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL822869 0.87 HTT (0.73) HTTL3MBTL1TDP1SMN1; SMN2POLB
SCHEMBL822846 0.87 LMNA (0.59) HTTSMN1; SMN2POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8916672-B2 Transparent polyarylene ether polymer with high heat resistance and method for preparing the same ICUF-HYU (Industry-University Cooperation Foundation Hanyang University) (KR) 2014-12-23 US disclosed
US-20120130041-A1 Transparent Polyarylene Ether Polymer With High Heat Resistance And Method For Preparing The Same IUCF-HYU (Industry-University Coperation Foundatio Hanyang University (KR) 2012-05-24 US disclosed