Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147786 | 0.89 | ALDH1A1 (0.44) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL5146469 | 0.89 | IDO1 (0.47) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL8767282 | 0.88 | MAPT (0.43) | IDO1ALDH1A1TSHRMDM2MAT2A | |
| SCHEMBL5144846 | 0.87 | KCNH2 (0.44) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL9185414 | 0.87 | IDO1 (0.40) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL9185418 | 0.87 | IDO1 (0.40) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL9060709 | 0.87 | ESR2 (0.47) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL13480380 | 0.87 | ESR2 (0.47) | IDO1ALDH1A1TSHRMDM2KMT2A | |
| SCHEMBL8767786 | 0.85 | MAPT (0.41) | IDO1ALDH1A1TSHRMDM2SMN1; SMN2 | |
| SCHEMBL8767312 | 0.85 | MAPT (0.41) | IDO1ALDH1A1TSHRMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |