Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.68 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.68 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.64 |
| ▸ | SELE | P16581 | 3/20 | 0.64 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440669 | 0.99 | MPO (0.69) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL6568731 | 0.91 | MPO (0.59) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL9247114 | 0.90 | MPO (0.56) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL9371455 | 0.89 | MPO (0.57) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL10372239 | 0.88 | MPO (0.55) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL9375225 | 0.88 | ICAM1 (0.57) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL10373579 | 0.87 | MPO (0.54) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL9246120 | 0.86 | MPO (0.52) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL10372978 | 0.86 | MPO (0.52) | MPOCYSLTR1ICAM1SELEVCAM1 | |
| SCHEMBL9371073 | 0.86 | EDNRA (0.66) | MPOCYSLTR1ICAM1SELEVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789569-A2 | USE OF BENZOTHIOPHENES AND BENZOFURANS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INFLAMMATION ASSAY METHOD | WARNER-LAMBERT COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1995002406-A2 | USE OF BENZOTHIOPHENES AND BENZOFURANS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INFLAMMATION ASSAY METHOD | WARNER-LAMBERT COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |