Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767819 | 0.97 | OPRL1 (0.37) | OPRL1ESR2ALOX5 | |
| SCHEMBL8767813 | 0.97 | OPRL1 (0.37) | OPRL1ESR2ALOX5 | |
| SCHEMBL8767808 | 0.97 | OPRL1 (0.37) | OPRL1ESR2ALOX5 | |
| SCHEMBL21581477 | 0.95 | ESR2 (0.36) | OPRL1ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL8768400 | 0.95 | OPRL1 (0.39) | OPRL1ESR2ESR1CYP3A4CYP2D6 | |
| SCHEMBL8768409 | 0.95 | OPRL1 (0.39) | OPRL1ESR2ESR1CYP3A4CYP2D6 | |
| SCHEMBL8768502 | 0.94 | SIGMAR1 (0.37) | OPRL1ESR2ALOX5 | |
| SCHEMBL8767048 | 0.94 | OPRL1 (0.35) | OPRL1ESR2ALOX5ESR1CYP3A4 | |
| SCHEMBL19720364 | 0.93 | OPRL1 (0.40) | OPRL1ESR2ESR1CYP3A4CYP2D6 | |
| SCHEMBL8767734 | 0.92 | SIGMAR1 (0.40) | OPRL1ESR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |