Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17293790 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL8767253 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL10717055 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL23909069 | 0.81 | CCNB2 (0.42) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL18265864 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL19575376 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| Phthalic Anhydride SCHEMBL27856846 | 0.78 | TDP1 (0.64) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL15473352 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL11215773 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL11215775 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009867-A | — | — | None | — | — | JP | disclosed |
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
| US-7314879-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314879-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7186715-B2 | Piperazine- and piperidine-derivatives as melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-03-06 | — | — | US | disclosed |
| EP-0652213-B1 | Method for producing alkyl 3-phthalidylideneacetate | SUMIKA FINE CHEMICALS CO LTD (JP) | 1997-08-27 | — | — | EP | disclosed |
| US-5508446-A | Method for producing alkyl 3-phthalidylideneacetate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0652213-A1 | Method for producing alkyl 3-phthalidylideneacetate | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |
| EP-0331314-B1 | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate | PFIZER (US) | 1994-04-06 | — | — | EP | disclosed |
| US-4940791-A | Process for the production of phthalazineacetic acid ester derivatives and a novel hydrazine containing intermediate | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4940791-A | Process for the production of phthalazineacetic acid ester derivatives and a novel hydrazine containing intermediate | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |
| US-4904782-A | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate | PFIZER INC. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4904782-A | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate | PFIZER INC. (US) | 1990-02-27 | — | — | US | disclosed |
| JP-H029867-A | PRODUCTION OF PHTHALAZINEACETIC ACID ESTER DERIVATIVE AND NOVEL INTERMEDIATE | PFIZER INC | 1990-01-12 | — | — | JP | disclosed |
| EP-0331314-A2 | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate | PFIZER INC. (US) | 1989-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | ALDH1A1 944/4885KDM4E 3835/4885HPGD 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.