Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL10779794 | 0.92 | HDAC4 (0.42) | HDAC4CYP2D6PDK2ACHECYP2C9 | |
| SCHEMBL8766538 | 0.86 | ACHE (0.35) | HDAC4ACHECYP2C9CYP2C19PDE7A | |
| SCHEMBL8765847 | 0.86 | HDAC4 (0.44) | HDAC4CYP2D6PDK2MAPTMEN1 | |
| SCHEMBL8766466 | 0.81 | HDAC4 (0.44) | HDAC4CYP2D6PDK2CYP2C9MAPT | |
| SCHEMBL8766383 | 0.79 | HDAC4 (0.56) | HDAC4CYP2D6PDK2POLBPDE7A | |
| SCHEMBL8766329 | 0.79 | HDAC4 (0.39) | HDAC4CYP2D6PDK2CYP2C9CYP2C19 | |
| SCHEMBL8766477 | 0.78 | HDAC4 (0.38) | HDAC4CYP2D6 | |
| SCHEMBL8767261 | 0.77 | HDAC4 (0.38) | HDAC4CYP2D6 | |
| SCHEMBL8766110 | 0.77 | HDAC4 (0.38) | HDAC4CYP2D6 | |
| SCHEMBL8766390 | 0.77 | HDAC4 (0.38) | HDAC4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |