Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.72 |
| ▸ | RARG | P13631 | 6/20 | 0.72 |
| ▸ | RARA | P10276 | 5/20 | 0.72 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766441 | 1.00 | RARB (0.72) | RARBRARGRARAHSD17B2MAPT | |
| SCHEMBL9076395 | 1.00 | RARB (0.72) | RARBRARGRARAHSD17B2MAPT | |
| SCHEMBL21376220 | 0.85 | HSD17B2 (0.61) | RARBRARGRARAHSD17B2MAPT | |
| SCHEMBL8766433 | 0.84 | RARG (1.00) | RARBRARGRARAKDM4ELMNA | |
| SCHEMBL6372828 | 0.84 | RARG (1.00) | RARBRARGRARAKDM4ELMNA | |
| SCHEMBL6372834 | 0.84 | RARG (1.00) | RARBRARGRARAKDM4ELMNA | |
| SCHEMBL8766137 | 0.82 | RARA (0.73) | RARBRARGRARAGAANQO2 | |
| SCHEMBL8766130 | 0.82 | RARA (0.73) | RARBRARGRARAGAANQO2 | |
| SCHEMBL8765888 | 0.80 | RARA (0.73) | RARBRARGRARANQO2PTGS1 | |
| SCHEMBL8765882 | 0.80 | RARA (0.73) | RARBRARGRARANQO2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | claimed |
| US-5547983-A | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1996-08-20 | — | — | US | disclosed |