SCHEMBL8767310

SCHEMBL8767310

CC(C)(Oc1ccc(OCCSc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.47
PPARD Q03181 12/20 0.47
PPARG P37231 11/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylamine SCHEMBL8924062 0.96 PPARA (0.45) PPARAPPARDPPARG
SCHEMBL8768773 0.87 PPARA (0.54) PPARAPPARDPPARG
SCHEMBL8923974 0.86 PPARG (0.52) PPARAPPARDPPARG
SCHEMBL8767430 0.85 PPARA (0.56) PPARAPPARDPPARG
SCHEMBL8767368 0.84 PPARG (0.42) PPARAPPARDPPARG
SCHEMBL8767800 0.84 PPARA (0.52) PPARAPPARDPPARG
SCHEMBL8923383 0.83 PPARA (0.54) PPARAPPARDPPARG
SCHEMBL8923438 0.82 PPARA (0.44) PPARAPPARDPPARG
SCHEMBL8924642 0.80 ADRB3 (0.43) PPARAPPARDPPARG
SCHEMBL8924650 0.80 ADRB3 (0.43) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621255-B1 Substituted phenoxy-isobutyric acids and esters ADIR (FR) 1997-08-20 EP disclosed
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US disclosed
EP-0621255-A1 Substituted phenoxy-isobutyric acids and esters ADIR ET COMPAGNIE (FR) 1994-10-26 EP disclosed