SCHEMBL8767430

SCHEMBL8767430

CC(C)(Oc1ccc(CCCSc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 15/20 0.56
PPARG P37231 13/20 0.52
PPARD Q03181 8/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923383 0.96 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL8768773 0.93 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL8767800 0.86 PPARA (0.52) PPARAPPARGPPARD
SCHEMBL8925210 0.86 PPARA (0.64) PPARAPPARGPPARD
SCHEMBL8767310 0.85 PPARA (0.47) PPARAPPARGPPARD
SCHEMBL8039541 0.84 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL8923846 0.83 PPARG (0.59) PPARAPPARGPPARD
Tert-Butylamine SCHEMBL8924062 0.82 PPARA (0.45) PPARAPPARGPPARD
SCHEMBL8924029 0.81 PPARG (0.64) PPARAPPARGPPARD
SCHEMBL8923120 0.81 PPARA (0.53) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621255-B1 Substituted phenoxy-isobutyric acids and esters ADIR (FR) 1997-08-20 EP claimed
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US disclosed