Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767510 | 0.91 | GRM5 (0.41) | GRM5P2RY14KMT2AUSP30 | |
| SCHEMBL8767914 | 0.88 | P2RY14 (0.33) | EGLN1EGLN3P2RY14 | |
| SCHEMBL8768432 | 0.88 | GRM5 (0.34) | GRM5USP30 | |
| SCHEMBL8767254 | 0.87 | GRM5 (0.35) | GRM5 | |
| SCHEMBL10527807 | 0.83 | ESR2 (0.46) | GRM5EGLN1EGLN3P2RY14MEN1 | |
| SCHEMBL9409313 | 0.83 | CYP2C9 (0.44) | GRM5EGLN1EGLN3MEN1KMT2A | |
| SCHEMBL9409308 | 0.83 | CYP2C9 (0.44) | GRM5EGLN1EGLN3MEN1KMT2A | |
| SCHEMBL9409316 | 0.83 | CYP2C9 (0.44) | GRM5EGLN1EGLN3MEN1KMT2A | |
| SCHEMBL8767567 | 0.82 | HTR2A (0.39) | MEN1KMT2AUSP30 | |
| SCHEMBL23366152 | 0.80 | HTR2A (0.38) | MEN1KMT2AUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |