Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.70 |
| ▸ | DRD3 | P35462 | 12/20 | 0.70 |
| ▸ | DRD4 | P21917 | 5/20 | 0.70 |
| ▸ | HTR1D | P28221 | 3/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767680 | 1.00 | DRD2 (0.70) | DRD2DRD3DRD4HTR1DHTR1B | |
| Bromide SCHEMBL7333392 | 0.99 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7331890 | 0.99 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Bromide SCHEMBL7333395 | 0.99 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7331896 | 0.99 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| SCHEMBL9295381 | 0.92 | DRD2 (0.72) | DRD2DRD3DRD4 | |
| Bromide SCHEMBL7396338 | 0.91 | DRD2 (0.70) | DRD2DRD3DRD4 | |
| Bromide SCHEMBL7401962 | 0.91 | DRD2 (0.70) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7271841 | 0.88 | DRD2 (0.59) | DRD2DRD3DRD4 | |
| SCHEMBL7933887 | 0.86 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781268-A1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| EP-0719252-A1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1996-07-03 | — | — | EP | disclosed |