Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148655 | 0.82 | KDM4E (0.58) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL18483380 | 0.81 | KDM4E (0.48) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL20110465 | 0.81 | KDM4E (0.48) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL28960097 | 0.80 | KDM4E (0.56) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL30104195 | 0.80 | KDM4E (0.56) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13377770 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL10767350 | 0.77 | MEN1 (0.56) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL2439328 | 0.77 | NPC1 (0.52) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL5026243 | 0.77 | KDM4E (0.48) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5017827 | 0.75 | RPS6KB2 (0.52) | SMN1; SMN2MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513863-B1 | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates | NITTO BOSEKI CO LTD (JP) | 1997-09-03 | — | — | EP | disclosed |
| EP-0350915-B1 | Substrates for determination of enzyme activity | NITTO BOSEKI CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| EP-0513863-A1 | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates | NITTO BOSEKI CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
| EP-0224255-B1 | SYNTHETIC PEPTIDIC SUBSTRATE FOR DETERMINATION OF TRYPSIN AND ALPHA 1-ANTITRYPSIN | NITTO BOSEKI CO., LTD. (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-5116941-A | PEPTIDE SUBSTRATES FOR DETERMINATION OF ENZYME ACTIVITY | NITTO BOSEKI CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5115099-A | Modified tripeptides as substrates for determination of enzyme activity | NITTO BOSEKI CO., LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0224254-B1 | A NOVEL SUBSTRATE FOR PLASMA KALLIKREIN AND A METHOD FOR MEASURING BIOLOGICAL COMPONENTS USING THE SAME | NITTO BOSEKI CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-5063152-A | Synthetic peptidic substrate for determination of trypsin and α1 | NITTO BOSEKI CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0167980-B1 | NOVEL SUBSTRATES FOR USE IN MEASURING THE CONCENTRATION OF KALLIKREIN IN URINE | NITTO BOSEKI CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0350915-A2 | Substrates for determination of enzyme activity | NITTO BOSEKI CO., LTD. (JP) | 1990-01-17 | — | — | EP | disclosed |
| US-4894438-A | TRIPEPTIDES; ANTIINFLAMMATORY AGENTS | NITTO BOSEKI CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0347734-A2 | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates | NITTO BOSEKI CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| US-4816562-A | Novel substrate for plasma kallikrein and a method for measuring biological components using the same | NITTO BOSEKI CO., LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0170797-B1 | NOVEL SUBSTRATE FOR DETERMINING THE ACTIVITY OF BLOOD COAGULATION FACTOR XA (STUART-PROWER FACTOR) | NITTO BOSEKI CO., LTD. (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |
| EP-0224255-A2 | Synthetic peptidic substrate for determination of trypsin and alpha 1-antitrypsin | NITTO BOSEKI CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |
| EP-0224254-A2 | A novel substrate for plasma kallikrein and a method for measuring biological components using the same | NITTO BOSEKI CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |
| US-4650753-A | Novel substrates for use in measuring the concentration of kallikrein in urine | NITTO BOSEKI CO., LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| US-4622389-A | Novel substrate for determining the activity of blood coagulation factor Xa (Stuart-Prower factor) | Nitto Poseki Co., Ltd. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0077124-B1 | NOVEL SUBSTRATES FOR MEASURING PLASMIN | NITTO BOSEKI CO., LTD. (JP) | 1985-03-27 | — | — | EP | disclosed |