SCHEMBL20110465

SCHEMBL20110465

Cc1nc(C)nc(-c2cccs2)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.48
MAPT P10636 5/20 0.48
ALDH1A1 P00352 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
MEN1 O00255 3/20 0.48
HPGD P15428 3/20 0.48
KMT2A Q03164 3/20 0.48
ADORA3 P0DMS8 3/20 0.46
ADORA2A P29274 3/20 0.46
NPC1 O15118 6/20 0.45
RAB9A P51151 6/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
LMNA P02545 3/20 0.45
MAPK1 P28482 2/20 0.45
TP53 P04637 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
ADORA1 P30542 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18483380 0.96 KDM4E (0.48) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL24689618 0.85 L3MBTL1 (0.66) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL19148655 0.84 KDM4E (0.58) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL30104195 0.81 KDM4E (0.56) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL28960097 0.81 KDM4E (0.56) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL8767745 0.81 SMN1; SMN2 (0.50) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL21398159 0.77 KDM4E (0.57) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL18482816 0.76 NPC1 (0.64) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL5026243 0.74 KDM4E (0.48) KDM4EMAPTALDH1A1L3MBTL1TDP1
SCHEMBL4011784 0.74 HSD17B10 (0.52) KDM4EMAPTALDH1A1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074308-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240074308-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-20230189641-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189641-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20180123049-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-03 US disclosed
US-20180123049-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189641-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 KDM4E 2539/4885MAPT 756/4885ALDH1A1 884/4885
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 KDM4E 2539/4885MAPT 756/4885ALDH1A1 884/4885
US-20180123049-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 KDM4E 2539/4885MAPT 756/4885ALDH1A1 884/4885
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same TEAD2, TEAD3, TEAD4 KDM4E 2539/4885MAPT 756/4885ALDH1A1 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.