Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.62 |
| ▸ | PPARG | P37231 | 9/20 | 0.62 |
| ▸ | PPARD | Q03181 | 5/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926594 | 0.88 | PPARA (0.52) | PPARAPPARGPPARDSOAT1HTT | |
| SCHEMBL8925066 | 0.82 | PPARA (0.85) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768931 | 0.81 | PPARA (0.52) | PPARAPPARGPPARDHTTNPC1 | |
| SCHEMBL14345218 | 0.78 | PPARA (0.61) | PPARAPPARGPPARDHTTNPC1 | |
| SCHEMBL8159724 | 0.77 | PPARA (1.00) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL9265603 | 0.74 | HTT (0.68) | SOAT1HTTRAB9A | |
| SCHEMBL14345568 | 0.74 | PPARA (0.56) | PPARAPPARGPPARDHTTNPC1 | |
| SCHEMBL8768601 | 0.72 | PPARG (0.70) | PPARAPPARGPPARDSOAT1HTT | |
| SCHEMBL8767793 | 0.72 | POLB (0.53) | PPARAPPARGPPARDHTTNPC1 | |
| SCHEMBL14345276 | 0.70 | PPARA (0.53) | PPARAPPARGPPARDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |