Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924202 | 0.88 | TSHR (0.47) | PPARAALDH1A1PPARGPPARDGAA | |
| SCHEMBL8924339 | 0.85 | GAA (0.52) | PPARAALDH1A1PPARGPPARDGAA | |
| SCHEMBL8767827 | 0.84 | GAA (0.52) | PPARAALDH1A1PPARGPPARDGAA | |
| SCHEMBL8767679 | 0.82 | PPARA (0.59) | PPARAPPARGPPARDGAAHTT | |
| SCHEMBL8767784 | 0.82 | PPARA (0.61) | PPARAPPARGPPARDGAAHTT | |
| SCHEMBL8767727 | 0.82 | PPARA (0.61) | PPARAPPARGPPARDGAAHTT | |
| SCHEMBL8768686 | 0.82 | PPARA (0.61) | PPARAPPARGPPARDGAAHTT | |
| SCHEMBL8767780 | 0.81 | PPARA (0.62) | PPARAPPARGPPARDGAAHTT | |
| SCHEMBL8768167 | 0.81 | PPARA (0.57) | PPARAALDH1A1PPARGPPARDGAA | |
| SCHEMBL8925777 | 0.79 | PPARA (0.62) | PPARAALDH1A1PPARGPPARDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |