Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21649123 | 0.87 | MAOA (0.44) | GRIA1GRIA2GRIA3USP30MAOA | |
| SCHEMBL8768480 | 0.87 | MAOA (0.44) | GRIA1GRIA2GRIA3USP30MAOA | |
| SCHEMBL7902526 | 0.86 | MEN1 (0.52) | ESR2GRIA1GRIA2GRIA3USP30 | |
| SCHEMBL9498967 | 0.86 | MEN1 (0.52) | ESR2GRIA1GRIA2GRIA3USP30 | |
| SCHEMBL7509846 | 0.86 | MEN1 (0.52) | ESR2GRIA1GRIA2GRIA3USP30 | |
| SCHEMBL7902520 | 0.86 | MEN1 (0.52) | ESR2GRIA1GRIA2GRIA3USP30 | |
| SCHEMBL8730878 | 0.85 | MAOA (0.47) | GRIA1GRIA2GRIA3USP30MAOA | |
| SCHEMBL8730882 | 0.85 | MAOA (0.47) | GRIA1GRIA2GRIA3USP30MAOA | |
| SCHEMBL13621591 | 0.85 | GRIA1 (0.46) | ESR2GRIA1GRIA2GRIA3USP30 | |
| SCHEMBL10778635 | 0.84 | MEN1 (0.44) | ESR2GRIA1GRIA2GRIA3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |