SCHEMBL876795

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL876796	1.00	ACACB (0.35)	ACACBOPRK1PDE4BPDE4APDE4C
	SCHEMBL2139553	0.85	ACACB (0.40)	ACACBPDE4BPDE4APDE4CPDE4D
	SCHEMBL2139548	0.85	ACACB (0.40)	ACACBPDE4BPDE4APDE4CPDE4D
	SCHEMBL2138353	0.83	OPRK1 (0.42)	OPRK1PDE4BPDE4D
	SCHEMBL2138363	0.83	OPRK1 (0.42)	OPRK1PDE4BPDE4D
	SCHEMBL682962	0.82	KDM4E (0.40)	ACACBPDE4BPDE4APDE4CPDE4D
	SCHEMBL877167	0.81	PDE4D (0.44)	OPRK1PDE4BPDE4APDE4CPDE4D
	SCHEMBL877168	0.81	PDE4D (0.44)	OPRK1PDE4BPDE4APDE4CPDE4D
	SCHEMBL877637	0.79	PDE4B (0.42)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL683342	0.79	PDE4B (0.42)	PDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.