Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8503522 | 0.98 | CES2 (0.53) | CES2ITGB3ITGAVGAASLC9A1 | |
| SCHEMBL8768143 | 0.90 | CES2 (0.44) | CES2ITGB3ITGAVGAASLC9A1 | |
| SCHEMBL8768325 | 0.88 | CES2 (0.43) | CES2ITGB3ITGAVGAASLC9A1 | |
| Hydrochloric Acid SCHEMBL8956178 | 0.88 | CES2 (0.43) | CES2ITGB3ITGAVGAASLC9A1 | |
| Hydrochloric Acid SCHEMBL8504155 | 0.88 | CES2 (0.43) | CES2ITGB3ITGAVGAASLC9A1 | |
| SCHEMBL8170162 | 0.88 | CES2 (0.43) | CES2ITGB3ITGAVGAASLC9A1 | |
| Hydrochloric Acid SCHEMBL8503859 | 0.87 | CES2 (0.42) | CES2ITGB3ITGAVGAASLC9A1 | |
| Hydrochloric Acid SCHEMBL8506921 | 0.87 | HTR2B (0.45) | CES2ITGB3ITGAVGAASLC9A1 | |
| Hydrochloric Acid SCHEMBL8506641 | 0.87 | CES2 (0.42) | CES2ITGB3ITGAVGAASLC9A1 | |
| SCHEMBL8177945 | 0.84 | SLC9A5 (0.41) | CES2ITGB3ITGAVGAASLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612723-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicament, as inhibitor of the cellular Na+/H+ exchange or as diagnostic agent and medicament containing them | HOECHST AG (DE) | 1997-08-27 | — | — | EP | claimed |