Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 5/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767998 | 1.00 | ESR1 (0.55) | ESR1ESR2ELANEMAPTLMNA | |
| SCHEMBL5692795 | 0.93 | HSD17B10 (0.65) | ESR1ESR2ELANEMAPTLMNA | |
| SCHEMBL5692793 | 0.93 | HSD17B10 (0.65) | ESR1ESR2ELANEMAPTLMNA | |
| SCHEMBL7027310 | 0.91 | ESR1 (0.53) | ESR1ESR2ELANEMAPTLMNA | |
| Fenabutene SCHEMBL2111368 | 0.82 | ELANE (0.60) | ESR1ELANEMAPTLMNAMEN1 | |
| Fenabutene SCHEMBL28884547 | 0.82 | ELANE (0.60) | ESR1ELANEMAPTLMNAMEN1 | |
| SCHEMBL872233 | 0.82 | MAPT (0.59) | ESR1ELANEMAPTLMNAMEN1 | |
| Fenabutene SCHEMBL28884548 | 0.82 | ELANE (0.60) | ESR1ELANEMAPTLMNAMEN1 | |
| SCHEMBL5356686 | 0.82 | MAPT (0.51) | ESR1ELANEMAPTLMNAMEN1 | |
| SCHEMBL5356681 | 0.82 | MAPT (0.51) | ESR1ELANEMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789722-A1 | POLYCARBONATE AND POLYESTER COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5614599-A | STILBENEDIOL, MELT PROCESSABILITY, MOLDINGS | THE DOW CHEMICAL COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1996013539-A1 | POLYCARBONATE AND POLYESTER COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |