Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL23152272 | 0.93 | MAPT (0.53) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL10453434 | 0.84 | MAPT (0.56) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2451780 | 0.83 | MAPT (0.81) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL11354408 | 0.83 | MAPT (0.81) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL10941162 | 0.83 | MAPT (0.81) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL8767998 | 0.82 | ESR1 (0.55) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL8767995 | 0.82 | ESR1 (0.55) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL1100398 | 0.82 | AKR1C3 (0.60) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL1100400 | 0.82 | AKR1C3 (0.60) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL269329 | 0.82 | LMNA (0.80) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008248-A1 | REACTIVE MATERIAL AND THIN FILM PRODUCTION METHOD | 株式会社ADEKA | 2023-02-02 | — | — | WO | disclosed |
| WO-2021195361-A2 | COMPOSITIONS AND METHODS FOR MODULATING MYOSIN SUBFRAGMENT-2 COILED COIL STABILITY AND METHODS FOR USING THEM | UNIVERSITY OF NORTH TEXAS (US) | 2021-09-30 | — | — | WO | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-109310739-A | Novel antigens and methods of use thereof | 内恩疗法公司 | 2019-02-05 | — | — | CN | disclosed |
| US-20170073337-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| CN-106459960-A | Conditionally active biological proteins | 生物蛋白有限公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-2016191263-A1 | THERAPY AND KIT FOR THE PREVENTION AND TREATMENT OF CYSTIC FIBROSIS | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2016-12-01 | — | — | WO | disclosed |
| EP-3094346-A2 | VISTA ANTAGONIST AND METHODS OF USE | The Trustees Of Dartmouth College (US) | 2016-11-23 | — | — | EP | disclosed |
| EP-3074030-A1 | METHOD FOR MITIGATING OR ALLEVIATING SYNAPTIC AND COGNITIVE DEFICITS | Trustees of Dartmouth College (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015109340-A2 | VISTA ANTAGONIST AND METHODS OF USE | NOELLE RANDOLPH J (US) | 2015-07-23 | — | — | WO | disclosed |
| CN-101646767-A | Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them | VERENIUM CORP US | 2010-02-10 | — | — | CN | disclosed |
| EP-1771728-A2 | METHODS AND COMPOSITIONS FOR RISK STRATIFICATION | The Board of Trustees of The Leland Stanford Junior University (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1648490-A2 | PEPTIDES AND PEPTIDOMIMETICS HAVING IMMUNE-MODULATING, ANTI-INFLAMMATORY, AND ANTI-VIRAL ACTIVITY | Canbas Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| WO-2006012507-A2 | METHODS AND COMPOSITIONS FOR RISK STRATIFICATION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-2004112820-A2 | PEPTIDES AND PEPTIDOMIMETICS HAVING IMMUNE-MODULATING, ANTI-INFLAMMATORY, AND ANTI-VIRAL ACTIVITY | CANBAS CO., LTD. (JP) | 2004-12-29 | — | — | WO | disclosed |
| WO-1994003601-A9 | CLONING, EXPRESSION AND USES FOR NEUROCAN AS A CHONDROITIN SULFATE PROTEOGLYCAN | — | 1994-03-31 | — | — | WO | disclosed |
| WO-1994003601-A2 | CLONING, EXPRESSION AND USES FOR NEUROCAN AS A CHONDROITIN SULFATE PROTEOGLYCAN | NEW YORK UNIVERSITY (US) | 1994-02-17 | — | — | WO | disclosed |
| US-4933495-A | Process for the production of 3-mono or 3,5 dihalogenated 4-acetoxystyrene, its polymerization, and hydrolysis | HOECHST CELANESE CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| US-4868257-A | Process for the production of 3-mono or 3,5 disubstituted-4-acetoxystyrene, its polymerization | HOECHST CELANESE CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868256-A | Process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene its polymerization, and hydrolysis | HOECHST CELANESE (US) | 1989-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073337-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | BACE1, BACE2, APP | MAPT 198/4885MEN1 3863/4885KMT2A 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.