Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.46 |
| ▸ | PPARA | Q07869 | 15/20 | 0.45 |
| ▸ | PPARD | Q03181 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922447 | 0.88 | PPARA (0.51) | PPARGPPARAPPARDCYP1A2CYP3A4 | |
| SCHEMBL8767368 | 0.88 | PPARG (0.42) | PPARGPPARAPPARD | |
| SCHEMBL8923974 | 0.82 | PPARG (0.52) | PPARGPPARAPPARDMEN1CYP1A2 | |
| SCHEMBL8768660 | 0.78 | CYP3A4 (0.39) | MEN1CYP3A4KMT2A | |
| SCHEMBL8767371 | 0.78 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL8921601 | 0.77 | PPARA (0.46) | PPARGPPARACYP1A2CYP3A4MAPT | |
| SCHEMBL8921956 | 0.77 | PPARA (0.46) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL8924029 | 0.73 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL9234359 | 0.71 | POLB (0.34) | PPARGPPARAPPARDMAPT | |
| SCHEMBL8923846 | 0.71 | PPARG (0.59) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| US-5627205-A | ANTILIPEMIC AGENTS AND ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |