SCHEMBL8924029

SCHEMBL8924029

CC(C)(Oc1ccc(CCOc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.64
PPARA Q07869 15/20 0.63
PPARD Q03181 14/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923846 0.92 PPARG (0.59) PPARGPPARAPPARD
SCHEMBL8923974 0.90 PPARG (0.52) PPARGPPARAPPARD
SCHEMBL8925210 0.85 PPARA (0.64) PPARGPPARAPPARD
SCHEMBL8768773 0.83 PPARA (0.54) PPARGPPARAPPARD
SCHEMBL8619033 0.83 PPARA (0.54) PPARGPPARAPPARD
SCHEMBL8923120 0.82 PPARA (0.53) PPARGPPARAPPARD
SCHEMBL8767430 0.81 PPARA (0.56) PPARGPPARAPPARD
Tert-Butylamine SCHEMBL8924413 0.80 PPARA (0.45) PPARGPPARAPPARD
SCHEMBL8923383 0.79 PPARA (0.54) PPARGPPARAPPARD
SCHEMBL9517990 0.79 CA2 (0.55) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US disclosed