Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768125 | 1.00 | POLB (0.40) | POLBNQO2MTNR1AMTNR1BADRB3 | |
| SCHEMBL9443665 | 0.81 | ADRB3 (0.51) | POLBMTNR1AMTNR1BADRB3ALDH1A1 | |
| SCHEMBL9443701 | 0.81 | ADRB3 (0.51) | POLBMTNR1AMTNR1BADRB3ALDH1A1 | |
| SCHEMBL9443694 | 0.81 | ADRB3 (0.51) | POLBMTNR1AMTNR1BADRB3ALDH1A1 | |
| SCHEMBL8767229 | 0.79 | POLB (0.40) | POLBADRB3ALDH1A1GAAKDM4E | |
| SCHEMBL8767235 | 0.79 | POLB (0.40) | POLBADRB3ALDH1A1GAAKDM4E | |
| SCHEMBL8765787 | 0.79 | POLB (0.50) | POLBADRB3ALDH1A1GAAKDM4E | |
| SCHEMBL8767977 | 0.78 | NQO2 (0.40) | NQO2MTNR1AMTNR1BACHEKDM1A | |
| SCHEMBL8767970 | 0.78 | NQO2 (0.40) | NQO2MTNR1AMTNR1BACHEKDM1A | |
| SCHEMBL8767973 | 0.78 | NQO2 (0.40) | NQO2MTNR1AMTNR1BACHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |
| EP-0579833-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018461-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |