Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767229 | 1.00 | POLB (0.40) | POLBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9443694 | 0.81 | ADRB3 (0.51) | POLBALDH1A1GAAADRB3NPSR1 | |
| SCHEMBL9443701 | 0.81 | ADRB3 (0.51) | POLBALDH1A1GAAADRB3NPSR1 | |
| SCHEMBL9443665 | 0.81 | ADRB3 (0.51) | POLBALDH1A1GAAADRB3NPSR1 | |
| SCHEMBL8768125 | 0.79 | POLB (0.40) | POLBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8768133 | 0.79 | POLB (0.40) | POLBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8765787 | 0.79 | POLB (0.50) | POLBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8768732 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8768742 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL8767875 | 0.77 | HPGD (0.45) | POLBALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |