Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768990 | 0.89 | PPARA (0.50) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8925832 | 0.87 | PPARA (0.43) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8767877 | 0.81 | HDAC6 (0.59) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8768890 | 0.80 | PPARA (0.53) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8768641 | 0.79 | PPARA (0.51) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8768964 | 0.79 | PPARA (0.46) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8768980 | 0.79 | PPARA (0.50) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8925423 | 0.78 | PPARA (0.49) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL8768932 | 0.78 | HDAC6 (0.50) | PPARAPPARGPPARDHDAC3HDAC1 | |
| SCHEMBL8925569 | 0.77 | PPARA (0.43) | PPARAPPARGPPARDHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |